Multimodal brain imaging reveals structural differences in Alzheimer’s disease polygenic risk carriers_ A study in healthy young adultsImaging Alzheimer’s disease polygenic risk
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چکیده
Cite this article as: Sonya F. Foley, Katherine E. Tansey, Xavier Caseras, Thomas Lancaster, Tobias Bracht, Greg Parker, Jeremy Hall, Julie Williams and David Linden, Multimodal brain imaging reveals structural differences in Alzheimer’s disease polygenic risk carriers: A study in healthy young adultsImaging Alzheimer’s disease polygenic risk, Biological Psychiatry, http://dx.doi.org/10.1016/j.biopsych.2016.02.033
منابع مشابه
Multimodal Brain Imaging Reveals Structural Differences in Alzheimer’s Disease Polygenic Risk Carriers: A Study in Healthy Young Adults
BACKGROUND Recent genome-wide association studies have identified genetic loci that jointly make a considerable contribution to risk of developing Alzheimer's disease (AD). Because neuropathological features of AD can be present several decades before disease onset, we investigated whether effects of polygenic risk are detectable by neuroimaging in young adults. We hypothesized that higher poly...
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